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The EMSS has a large repository of mycoplasma-tested and cell-line authenticated cells available for in vivo or in vitro-leading-to-in vivo research. The EMSS can grow these or other established cell lines and provide all necessary cell culture products and mycoplasma screening.
EMSS provides some human optical reporter cell lines that have been transfected with GFP, RFP and luciferase for experimental purposes. These cell lines include breast, pancreatic and colon cancers and are bolded; Cell Lines & Tumor Types Listed Below.
The EMSS regularly tests all cell lines grown in-house for mycoplasma contamination and offers weekly testing for other investigators. Regular screening of cell lines for mycoplasma is extremely important. This is especially true when accepting any cell line from an outside source. Mycoplasma can alter virtually every property measured in cell cultures. Working with contaminated cultures may nullify all results. Recommended treatment methods can be provided in cases of mycoplasma contamination.
Consultation and training sessions are available. Session topics often range from how to solve contamination problems, to questions about cell growth, to cell culture techniques. Contact us about your topic interests and scheduling opportunities.
The EMSS can derive cell lines from patient samples.
In addition to maintaining a selection of authenticated cell lines, the EMSS can authenticate cell lines. Journals are enacting more stringent guidelines to ensure the accuracy of the research they publish. The EMSS can test a cell line from a pellet or grow and sample a pellet for testing and report the results.
The model of choice can be used, and assistance is available to help you select the most appropriate model for the investigation agent you are using. Specially requested cell lines or tumor chunks can be brought in-house if a desired model is not listed below. Note that the human optical reporter cell lines are bolded.
Cell Line Name
Gastrointestinal Stromal Tumor
Head & Neck
HL-60, K562/S, K562/MDR, KG-1, OCI-AML3
A-375, DH903, JH1308, KD1592, PS1273, WM1791C, LOX IMVI, SB-CL2, MDA-MB-435
8226/S, 8226/V, 8228/Dox40, ARH-77, ARHD60
A2780, A2780/ADR, NIH:OVCAR-3
Mouse Tumor Xenografts
Rat Tumor Xenografts