The overall objective of the Analytical Core Shared Service (ACSS) is to provide Arizona Cancer Center (AZCC) investigators with a dedicated facility and expertise in developing/implementing analytical procedures, designing sample collection schedules, developing proper sample handling and storage conditions, performing quantitative analysis of drug/chemical levels, and interpreting and analyzing data.
Specifically, the ACSS has the following aims:
- To provide AZCC investigators with support in the development of chromatography-based analytical methods;
- To provide AZCC investigators with support in routine quantitative analysis of clinical and pre-clinical samples;
- To provide consultation in pharmacokinetic trial design and pharmacokinetic and pharmacodynamic data analysis.
By continuing to provide state-of-the-art analytical and pharmacokinetic services, the ACSS laboratory should greatly augment pre-clinical drug discovery efforts and stimulate the incorporation of pharmacokinetic endpoints in clinical trials.
Core Personnel
H-H. Sherry Chow, Ph.D., Co-Director
schow@azcc.arizona.edu (520) 626-3358
Steven Stratton, Ph.D., Co-Director
sstratton@azcc.arizona.edu (520) 626-9295
Min-Jian Xu, M.D., Manager
mjxu@azcc.arizona.edu (520) 626-1386
Wade Chew, Research Technician
wchew@azcc.arizona.edu (520) 626-2331