I am a tenured Professor with appointments in the Department of Radiology and the College of Optical Sciences at the University of Arizona. I am a member of the Arizona Cancer Center and the Graduate Interdisciplinary Program in Biomedical Engineering. I am a physical chemist with 24 years of experience in molecular imaging and the development and application of advanced instrumentation for x-ray and gamma-ray imaging and spectroscopy, optical imaging and spectroscopy, and related methods for biomedical research. I am a founding member and Associate Director of the NIH-funded Center for Gamma-ray Imaging, and have been a project leader for the Center since its inception in 1999.
I have served as principal investigator, project leader, or co-investigator on federally- and industry-funded research projects including grants from the NCRR, NCI, and NIBIB institutes, and mentor graduate students working towards masters and PhD degrees. I have a broad physics, chemistry, and structural biology background, and teach graduate courses in the University of Arizona’s College of Optical Sciences on the physics and mathematics of imaging and spectroscopy. I also co-teach a graduate course in the Biomedical Engineering/Cancer Biology programs on radiochemistry and molecular imaging methods in drug discovery. I currently serve as co-chair of the NIH SBMIT(10) study section which handles SBIR proposals in the biomedical imaging field.
I have special expertise in the techniques required to develop and apply advanced x-ray and gamma-ray detectors, and commissioned SPECT and PET imaging systems. This includes the physics of scintillation and solid-state detectors, methods of optics, pulse-processing electronics, digital data acquisition, and data inversion/assessment/reconstruction with a variety of computational methods. I work closely with and advise Masters and PhD students to carry out fundamental research and develop hardware technologies as part of their thesis/disseration projects.
I will work closely with Dr. Barrett and the other CGRI project leaders and faculty members towards the successful completion of the specific aims in the core projects, collaborations, and service activities proposed in this P41 renewal application. I will meet with them on a regular basis, participate in the design of the research program, work with our students and staff to carry out experiments, help acquire and analyze data, and prepare relevant manuscripts and presentations that describe study findings.