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Laboratory of RNA-Protein Interactions
Dr. Woo received his PhD from the University of Minnesota, Twin Cities, and his undergraduate degree from the Korea University, Seoul, Korea. He did postdoctoral work at the Memorial Sloan-Kettering Cancer Center, New York.
His research goal is to understand the molecular mechanisms of RNA structurome formation. He is interested particularly in how RNA-Protein interaction determins the RNA secondary strucuture which regulates translation as well as deadenylation of mRNAs.
In translational reseach, he is interested in the molecular basis of metastasis in epithelial ovarian and breast cancers. Abnormal expression of proto-oncogenes c-fms and CSF-1 is an important prognostic factor. CSF-1 encodes colony stimulating factor-1 (CSF-1) and c-fms encodes receptor tyrosine kinase (CSF-1R), a sole receptor to CSF-1. His research focuses on post-transcriptional and translational regulation of c-fms and CSF-1 by means of RNA-Protein interactions and miRNAs.