Arizona Cancer Center researchers Raymond Nagle, MD, PhD, and Elizabeth Jacobs, PhD, have been selected as the 2009 recipients of the Sydney E. Salmon, MD, distinguished senior investigator award and distinguished junior investigator award, respectively.
The Salmon Awards are presented in memory of the Arizona Cancer Center’s founding director, Sydney E. Salmon, MD, whose birthday is May 8. Drs. Nagle and Jacobs will receive their awards and present their latest research findings on that day. The Salmon Awards recognize Arizona Cancer Center faculty members for their leadership in cancer research, grant support, publications, community service and clinical responsibilities.
Dr. Nagle is a professor of pathology, cell biology and anatomy and surgery at the University of Arizona, where he has been a faculty member since 1981. He has served as deputy director and interim director of the Arizona Cancer Center.
Dr. Nagle’s major research goals involve understanding various factors that allow prostate cancer cells to migrate from the site of origin in the prostate and spread to other sites such as bone. Using tissue staining and other molecular and pathological techniques, more appropriate therapies can be selected and new approaches can be discovered, aimed at preventing malignant invasion. Nagle’s National Cancer Institute (NCI)-funded prostate program project grant (R01) is in its 16th year.
He also has more than 28 funded grants and has authored more than 180 papers and abstracts in the area of solid tumor pathology and prostate cancer progression.
Dr. Jacobs is a cancer epidemiologist and assistant professor in the University of Arizona’s Mel and Enid Zuckerman College of Public Health. Her research has focused on the genetic, lifestyle and dietary factors associated with cancer risk. Dr. Jacobs received her post-doctoral training in cancer epidemiology and is
currently completing the final year of a K07 grant (cancer prevention and control for junior faculty research) from the NCI. The aims of the grant are to assess the associations between dietary vitamin D intake, its receptor and their role in the recurrence of colorectal adenomas, which are potential precursor lesions for colorectal cancer.
In 2008, Dr. Jacobs received an R01 research grant from NCI to investigate whether dietary vitamin D and circulating blood levels of vitamin D metabolites are related to breast cancer recurrence in the Women’s Healthy Eating and Living (WHEL) Study. Along with her collaborator, Peter Jurutka, PhD, of the UA College of Medicine – Phoenix. Dr. Jacobs is investigating molecular mechanisms of the cancer- fighting activity of vitamin D.